公开(公告)号：US20130165452A1

公开(公告)日：2013-06-27

申请号：US13774204

申请日：2013-02-22

Applicant: Pfizer Inc.

Inventor： John William Benbow ,  Jihong Lou ,  Jeffrey Allen Pfefferkorn ,  Meihua Mike Tu

IPC: C07D403/12 ,  C07D413/12 ,  C07D401/12

CPC classification number: C07D401/12 ,  C07D231/40 ,  C07D403/12 ,  C07D405/14 ,  C07D413/12 ,  C07D513/04

Abstract: The present invention provides Formula (1A) compounds that act as glucokinase activators; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by glucokinase. X, Y, Z, R1, R2, R3, and R4 are as described herein.

Abstract translation: 本发明提供作为葡糖激酶活化剂的式（1A）化合物; 其药物组合物; 以及治疗由葡萄糖激酶介导的疾病，病症或病症的方法。 X，Y，Z，R 1，R 2，R 3和R 4如本文所述。