公开(公告)号：US20250049802A1

公开(公告)日：2025-02-13

申请号：US18719456

申请日：2022-12-12

Applicant: Pfizer Inc.

Inventor： Stephen George DANN ,  Koleen Jill EISELE ,  Conglin FAN ,  Manfred KRAUS ,  Pei-Pei KUNG ,  Shikhar SHARMA ,  Hui WANG

IPC: A61K31/519 ,  A61K31/444 ,  A61K31/567 ,  A61P35/00

Abstract: The present disclosure relates to the treatment of cancer and/or cancer-associated disease. Certain aspects relate to the treatment of an individual having cancer or cancer-associated disease by administering to the individual a combination therapy of a first therapeutic agent that is an EZH2 inhibitor, a second therapeutic agent that is a CDK inhibitor, and a third therapeutic agent that is a selective estrogen receptor degrader.