公开(公告)号：US11529344B2

公开(公告)日：2022-12-20

申请号：US16762388

申请日：2018-11-09

Applicant: Pfizer Inc.

Inventor： Manfred Kraus ,  Pei-Pei Kung ,  Thomas Andrew Paul ,  Shikhar Sharma ,  Dominique Verhelle

IPC: A61K31/4725 ,  A61P35/00 ,  A61K33/243 ,  A61K31/357 ,  A61K31/4412 ,  A61K31/4433 ,  A61K31/4545 ,  A61K31/496 ,  A61K31/501 ,  A61K31/5355 ,  A61K39/395 ,  A61K45/06

Abstract: This invention relates to combination therapies comprising an EZH2 inhibitor and a chemotherapeutic agent, and associated pharmaceutical compositions, methods of treatment, and pharmaceutical uses.

公开(公告)号：US20200268740A1

公开(公告)日：2020-08-27

申请号：US16762388

申请日：2018-11-09

Applicant: Pfizer Inc.

Inventor： Manfred Kraus ,  Pei-Pei Kung ,  Thomas Andrew Paul ,  Shikhar Sharma ,  Dominique Verhelle

IPC: A61K31/4725 ,  A61K33/243 ,  A61K31/357 ,  A61K45/06 ,  A61P35/00 ,  A61K39/395 ,  A61K31/5355 ,  A61K31/4545 ,  A61K31/496 ,  A61K31/501 ,  A61K31/4433 ,  A61K31/4412

Abstract: This invention relates to combination therapies comprising an EZH2 inhibitor and a chemotherapeutic agent, and associated pharmaceutical compositions, methods of treatment, and pharmaceutical uses.