公开(公告)号：US08933095B2

公开(公告)日：2015-01-13

申请号：US14068707

申请日：2013-10-31

Applicant: Pfizer Inc.

Inventor： Amy Beth Dounay ,  Laura Ann McAllister ,  Vinod Dipak Parikh ,  Suobao Rong ,  Patrick Robert Verhoest

IPC: C07D235/02 ,  C07D403/00 ,  C07D231/56 ,  C07D487/00 ,  C07D471/04 ,  C07D487/04

CPC classification number: C07D471/04 ,  C07D487/04

Abstract: Compounds of Formula I: wherein X, Y, Z, R1, R2, R3, R4 are as defined herein, and pharmaceutically acceptable salts thereof, are described as useful for the treatment of cognitive deficits associated with schizophrenia and other psychiatric, neurodegenerative and/or neurological disorders in mammals, including humans.

Abstract translation: 式I化合物：其中X，Y，Z，R 1，R 2，R 3，R 4如本文所定义，及其药学上可接受的盐被描述为可用于治疗与精神分裂症和其他精神病学，神经变性和/ 或哺乳动物包括人类的神经障碍。