公开(公告)号：US20190135932A1

公开(公告)日：2019-05-09

申请号：US16245816

申请日：2019-01-11

申请人： Pfizer Inc. ,  Bristol-Myers Squibb Company

发明人： Jing MIN ,  Yanli WU ,  Rory F. FINN ,  Barrett R. THIELE ,  Wei LIAO ,  Ronald P. GLADUE ,  Arvind RAJPAL ,  Timothy J. PARADIS ,  Peter BRAMS ,  Brigitte DEVAUX ,  Yi WU ,  Kristopher TOY ,  Heidi N. LEBLANC ,  Haichun HUANG

IPC分类号： C07K16/28

摘要： The present disclosure provides isolated binding molecules that bind to the human OX40R, nucleic acid molecules encoding an amino acid sequence of the binding molecules, vectors comprising the nucleic acid molecules, host cells containing the vectors, methods of making the binding molecules, pharmaceutical compositions containing the binding molecules, and methods of using the binding molecules or compositions.

公开(公告)号：US20220002428A1

公开(公告)日：2022-01-06

申请号：US17373965

申请日：2021-07-13

申请人： Pfizer Inc. ,  Bristol-Myers Squibb Company

发明人： Jing MIN ,  Yanli WU ,  Rory F. FINN ,  Barrett R. THIELE ,  Wei LIAO ,  Ronald P. GLADUE ,  Arvind RAJPAL ,  Timothy J. PARADIS ,  Peter BRAMS ,  Brigitte DEVAUX ,  Yi WU ,  Kristopher TOY ,  Heidi N. LEBLANC ,  Haichun HUANG

IPC分类号： C07K16/28

摘要： The present disclosure provides isolated binding molecules that bind to the human OX40R, nucleic acid molecules encoding an amino acid sequence of the binding molecules, vectors comprising the nucleic acid molecules, host cells containing the vectors, methods of making the binding molecules, pharmaceutical compositions containing the binding molecules, and methods of using the binding molecules or compositions.