-
1.发明申请(4-Phenylimidazol-2-yl) Ethylamine Derivatives Useful As Sodium Channel Modulators 审中-公开（4-苯基咪唑-2-基）乙胺衍生物可用作钠通道调节剂公开(公告)号：US20140296313A1
公开(公告)日：2014-10-02
申请号：US14351893
申请日：2012-10-15
申请人： Pfizer Limited
IPC分类号： C07D405/06 , A61K31/4178
CPC分类号： C07D405/06 , A61K31/4178
摘要： The present invention is directed to imidazole derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new imidazole NaV1.8 modulators of formula (I): or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4 and R5 are as defined in the description. NaV1.8 modulators useful in the treatment of a wide range of disorders, particularly pain.
摘要翻译： 本发明涉及咪唑衍生物，其在医药中的用途，含有它们的组合物，其制备方法以及在这些方法中使用的中间体。 更具体地，本发明涉及式（I）的新的咪唑NaV1.8调节剂：或其药学上可接受的盐，其中R 1，R 2，R 3，R 4和R 5如说明书中所定义。 NaV1.8调节剂可用于治疗各种疾病，特别是疼痛。
-
2.发明授权(4-phenylimidazol-2-yl) ethylamine derivatives useful as sodium channel modulators 有权（4-苯基咪唑-2-基）乙胺衍生物，其用作钠通道调节剂公开(公告)号：US09079878B2
公开(公告)日：2015-07-14
申请号：US14351893
申请日：2012-10-15
申请人： Pfizer Limited
IPC分类号： A61K31/4178 , C07D405/06
CPC分类号： C07D405/06 , A61K31/4178
摘要： The present invention is directed to imidazole derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new imidazole NaV1.8 modulators of formula (I): or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4 and R5 are as defined in the description. NaV1.8 modulators are useful in the treatment of a wide range of disorders, particularly pain.
摘要翻译： 本发明涉及咪唑衍生物，其在医药中的用途，含有它们的组合物，其制备方法以及在这些方法中使用的中间体。 更具体地，本发明涉及式（I）的新的咪唑NaV1.8调节剂：或其药学上可接受的盐，其中R 1，R 2，R 3，R 4和R 5如说明书中所定义。 NaV1.8调节剂可用于治疗各种疾病，特别是疼痛。
-
搜索结果
2 条记录 (耗时 0.012 秒)
