公开(公告)号：US08889189B2

公开(公告)日：2014-11-18

申请号：US13652837

申请日：2012-10-16

申请人： Phares Pharmaceutical Research N.V.

发明人： Steve Leigh ,  Mathew Louis Steven Leigh ,  Peter Van Hoogevest ,  Daniel Streich ,  Jacques Quinton

IPC分类号： A61K9/14 ,  A61K9/08 ,  A61K9/10 ,  A61K47/12 ,  A61K47/44 ,  G01N33/15

CPC分类号： G01N33/15 ,  Y10S514/937 ,  Y10S514/943

摘要： There are described solid compositions or examining drug solubility comprising bile salts and phospholipids, optionally containing buffer components suitable for preparation of intestinal media that simulate the composition of the intestinal fluids in fasted and fed states.

摘要翻译： 描述了固体组合物或检查药物溶解度，其包含胆汁盐和磷脂，任选地含有适于制备肠培养基的缓冲组分，其模拟禁食和进食状态下肠液的组成。

公开(公告)号：US20130055831A1

公开(公告)日：2013-03-07

申请号：US13652837

申请日：2012-10-16

申请人： Phares Pharmaceutical Research N.V.

发明人： Steve Leigh ,  Mathew Louis Steven Leigh ,  Peter Van Hoogevest ,  Daniel Streich ,  Jacques Quinton

IPC分类号： G01N33/15

CPC分类号： G01N33/15 ,  Y10S514/937 ,  Y10S514/943

摘要： There are described solid compositions or examining drug solubility comprising bile salts and phospholipids, optionally containing buffer components suitable for preparation of intestinal media that simulate the composition of the intestinal fluids in fasted and fed states.

公开(公告)号：US20160299113A1

公开(公告)日：2016-10-13

申请号：US14546981

申请日：2014-11-18

申请人： PHARES PHARMACEUTICAL RESEARCH N.V.

发明人： Steve Leigh ,  Mathew Louis Steven Leigh ,  Peter Van Hoogevest ,  Daniel Streich ,  Jacques Quinton

IPC分类号： G01N33/15

CPC分类号： G01N33/15 ,  Y10S514/937 ,  Y10S514/943

摘要： There are described solid compositions or examining drug solubility comprising bile salts and phospholipids, optionally containing buffer components suitable for preparation of intestinal media that simulate the composition of the intestinal fluids in fasted and fed states.