公开(公告)号：US5766954A

公开(公告)日：1998-06-16

申请号：US635938

申请日：1996-04-26

申请人： Philip Antony Freedman ,  Timothy Graham Brockwell

发明人： Philip Antony Freedman ,  Timothy Graham Brockwell

IPC分类号： G01N31/00 ,  B01D59/44 ,  G01N27/62 ,  G01N30/02 ,  G01N30/72 ,  G01N30/84 ,  G01N30/88 ,  G01N31/12 ,  G01N33/28 ,  G01N33/00

CPC分类号： G01N30/84 ,  B01D59/44 ,  G01N31/12 ,  G01N33/2835 ,  G01N2030/025 ,  G01N2030/8405 ,  G01N30/7206 ,  Y10T436/22 ,  Y10T436/24 ,  Y10T436/25875

摘要： A continuous flow method of determining the quantitative isotopic composition of hydrogen comprised in a compound is disclosed, together with apparatus for carrying out the method. The method involves introducing the sample to be analysed into a flow of carrier gas which does not contain hydrogen, the carrier gas then being arranged to flow through a heated catalytic reactor which contain a chromium-based catalyst. The sample is pyrolysed in the catalytic reactor so as to form molecular hydrogen which is then analysed mass-spectrometrically. Preferably a gas chromatrograph is disposed before the catalytic reactor so that one or more components or a mixture may be separately analysed.

摘要翻译： PCT No.PCT / GB95 / 02192 Sec。 371日期：1996年4月26日 102（e）日期1996年4月26日PCT提交1995年9月15日PCT公布。 第WO96 / 08719号公报 日期：1996年3月21日公开了一种确定化合物中所含的氢的定量同位素组成的连续流动方法以及用于实施该方法的装置。 该方法包括将要分析的样品引入不含氢气的载气流中，然后将载气流经包含铬基催化剂的加热催化反应器。 样品在催化反应器中热解，形成分子氢，然后进行质谱分析。 优选地，气相色谱仪设置在催化反应器之前，使得可以单独分析一种或多种组分或混合物。

公开(公告)号：US07374054B2

公开(公告)日：2008-05-20

申请号：US10727858

申请日：2003-12-04

申请人： Timothy Graham Brockwell

发明人： Timothy Graham Brockwell

IPC分类号： B65D51/16 ,  B65D45/00 ,  B65D39/00 ,  G01N1/00

CPC分类号： B01L3/50825 ,  G01N35/1079

摘要： A vial closure device, a sample vial incorporating such a vial closure device, and certain methods of using such a vial and closure device. The vial and closure device are intended to contain a gaseous sample or a headspace gas present above a liquid or solid material, so that the gaseous sample or headspace gas can be conveniently analyzed, typically by means of an autosampler connected to an analytical instrument such as a mass spectrometer. Mass spectrometric methods of determining the isotopic concentration of hydrogen and oxygen comprised in aqueous samples contained in vials fitted with such closure devices are disclosed. The vial closure device comprises a hollow body member locatable in the mouth of a vial, and a first seal for making a substantially gas-tight seal between the exterior of said hollow body member and said vial. The hollow body member comprises an aperture and an aperture closing means for closing said aperture when required, and a second seal, through which a gas sampling means may be inserted. The aperture closing means is operable to open the aperture by the insertion of a gas sampling means through the second seal and is operable to close the aperture when the gas sampling means is withdrawn.

摘要翻译： 小瓶封闭装置，装有这种小瓶封闭装置的样品瓶，以及使用这种小瓶和封闭装置的某些方法。 小瓶和关闭装置旨在包含气体样品或存在于液体或固体材料上方的顶空气体，从而通常可以通过连接到分析仪器的自动进样器方便地分析气态样品或顶空气体，如 质谱仪 公开了测定包含在装有这种闭合装置的小瓶中的含水样品中的氢和氧的同位素浓度的质谱方法。 小瓶封闭装置包括可定位在小瓶口中的中空本体构件和用于在所述中空本体构件的外部和所述小瓶之间形成基本上气密密封的第一密封件。 中空本体构件包括孔和用于在需要时封闭所述孔的孔关闭装置，以及第二密封，气体取样装置可以插入其中。 孔关闭装置可操作以通过插入通过第二密封件的气体采样装置来打开孔，并且当取出气体取样装置时可操作以关闭孔。

公开(公告)号：US06715624B2

公开(公告)日：2004-04-06

申请号：US08967410

申请日：1997-11-11

申请人： Timothy Graham Brockwell

发明人： Timothy Graham Brockwell

IPC分类号： B65D4120

CPC分类号： B01L3/50825 ,  G01N35/1079

摘要： A vial closure device, a sample vial incorporating such a vial closure device, and certain methods of using such a vial and closure device. The vial and closure device are intended to contain a gaseous sample or a headspace gas present above a liquid or solid material, so that the gaseous sample or headspace gas can be conveniently analysed, typically by means of an autosampler connected to an analytical instrument such as a mass spectrometer. Mass spectrometric methods of determining the isotopic composition of hydrogen and oxygen comprised in aqueous samples contained in vials fitted with such closure devices are disclosed. The vial closure device comprises a hollow body member locatable in the mouth of a vial, and a first seal for making a substantially gas-tight seal between the exterior of said hollow body member and said vial. The hollow body member comprises an aperture and an aperture closing means for closing said aperture when required, and a second seal, through which a gas sampling means may be inserted. The aperture closing means is operable to open the aperture by the insertion of a gas sampling means through the second seal and is operable to close the aperture when the gas sampling means is withdrawn.

摘要翻译： 小瓶封闭装置，装有这种小瓶封闭装置的样品瓶，以及使用这种小瓶和封闭装置的某些方法。 小瓶和关闭装置旨在包含气体样品或存在于液体或固体材料上方的顶空气体，从而通常可以通过连接到分析仪器的自动进样器方便地分析气态样品或顶空气体，例如 质谱仪 公开了测定包含在装有这种闭合装置的小瓶中的含水样品中的氢和氧的同位素组成的质谱方法。 小瓶封闭装置包括可定位在小瓶口中的中空本体构件和用于在所述中空本体构件的外部和所述小瓶之间形成基本上气密密封的第一密封件。 中空本体构件包括孔和用于在需要时封闭所述孔的孔关闭装置，以及第二密封，气体取样装置可以插入其中。 孔关闭装置可操作以通过插入通过第二密封件的气体采样装置来打开孔，并且当取出气体取样装置时可操作以关闭孔。