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公开(公告)号:US20240317854A1
公开(公告)日:2024-09-26
申请号:US18550537
申请日:2022-03-17
申请人: Philip E. Brandish , Mei Chen , Andrey Loboda , Michael Nebozhyn, III , Cai Wu , Daping Zhang , Jie Zhang-Hoover
发明人: Philip E. Brandish , Mei Chen , Andrey Loboda , Michael Nebozhyn, III , Cai Wu , Daping Zhang , Jie Zhang-Hoover
IPC分类号: C07K16/28 , A61K31/337 , A61K31/7068 , A61K39/00 , A61K39/395 , A61P35/00
CPC分类号: C07K16/2803 , A61K31/337 , A61K31/7068 , A61K39/3955 , A61P35/00 , C07K16/2818 , A61K2039/505 , A61K2039/507 , A61K2039/545
摘要: This disclosure relates to methods for treating solid tumors in a patient identified as having metastatic triple negative breast cancer, glioblastoma, metastatic pancreatic ductal adenocarcinoma, metastatic soft tissue sarcoma, or metastatic non-squamous non-small cell lung carcinoma, comprising administering an anti-ILT3 antigen binding protein, or antigen binding fragment, and an anti-PD1 antigen binding protein, or antigen binding fragment, to the patient every three weeks (Q3W).