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公开(公告)号:US20080095767A1
公开(公告)日:2008-04-24
申请号:US11832553
申请日:2007-08-01
申请人: Philip JENNINGS , Anthony Doyle , Adam Clarke , Robert Gay
发明人: Philip JENNINGS , Anthony Doyle , Adam Clarke , Robert Gay
IPC分类号: A61K39/395 , C07K16/18
CPC分类号: C07K16/241 , C07K16/18 , C07K2317/24 , C07K2317/56 , C07K2317/76 , C07K2317/92
摘要: The present invention provides an antibody or antigen-binding portion thereof having a variable region comprising at least two complementarity determining regions (CDRs) and at least three framework regions. The the framework regions are, or are derived from New World primate framework regions, and at least one of the CDRs is a non-New World primate CDR.
摘要翻译: 本发明提供具有包含至少两个互补决定区(CDR)和至少三个框架区的可变区的抗体或其抗原结合部分。 框架区域是或来自新世界灵长类动物框架区域,并且至少一个CDR是非新世界灵长类动物区系。