-
公开(公告)号:US20060171959A1
公开(公告)日:2006-08-03
申请号:US10536606
申请日:2003-12-19
IPC分类号: A61K39/02 , A61K39/108 , C12N1/21
CPC分类号: C07K14/26 , A61K2039/522 , C07K14/21
摘要: A series of genes from Pseudomonas aeruginosa and Klebsiella are shown to encode products that are implicated in virulence. The identification of theses genes therefore allows attenuated microorganisms to be produced. Furthermore, the genes or their encoded products can be used to identify antimicrobial drugs, diagnostic methods for the identification of a pathogen-associated disease, and in the manufacture of vaccines.
摘要翻译: 来自铜绿假单胞菌和克雷伯菌的一系列基因显示出编码与毒力有关的产物。 因此,这些基因的鉴定允许产生减毒的微生物。 此外,基因或其编码产物可用于鉴定抗微生物药物,用于鉴定病原体相关疾病的诊断方法和疫苗的制造。