公开(公告)号：US11249056B1

公开(公告)日：2022-02-15

申请号：US17203991

申请日：2021-03-17

申请人： Piyush Govindbhai Patel ,  Jayrajsinh Sarvaiya

发明人： Piyush Govindbhai Patel ,  Jayrajsinh Sarvaiya

IPC分类号： G01N30/14 ,  G01N33/15 ,  G01N30/86 ,  G01N30/02

摘要： The present invention relates to dialysis based in vitro drug release study method which mainly involves the use of a dialysis cartridge (A), a dissolution vessel (B), a receiver media vessel (C) and tubing's on the inlet and outlet ports (D, E, F, G) of the cartridge. When the pharmaceuticals complex dosage form is added to the dissolution vessel, diffusion of the soluble drug through the membrane of the dissolution cartridge assists in determining the release of drug from the complex dosage form. This study can be done by various methods as required by the complex dosage form. If the dosage form needs to go through dissolution followed by diffusion, the setup as described in Experiment 1 is arranged and the study is performed accordingly and if the dosage form needs to go through diffusion step only, the setup as described in Experiment 2 is arranged and the study is performed accordingly.