公开(公告)号：US09207184B2

公开(公告)日：2015-12-08

申请号：US13874971

申请日：2013-05-01

申请人： Polymer Technology Systems, Inc.

发明人： Timothy Riley ,  Aniruddha Patwardhan ,  Frank LaDuca

IPC分类号： G01N21/78 ,  G01N33/92 ,  G01N33/48 ,  G01N21/77

CPC分类号： G01N33/92 ,  C12Q1/60 ,  G01N21/78 ,  G01N33/48 ,  G01N33/525 ,  G01N2021/7759 ,  G01N2021/7773

摘要： In one embodiment, a test strip for testing for cholesterol-related blood analytes in whole blood includes a red blood cell separation layer, the red blood cell separation layer separating red blood cells from a blood sample applied to the test strip as the blood sample flows downward through the red blood cell separation layer. The test strip further includes a reaction layer receiving the blood sample from the red blood cell separation layer, the reaction layer including POE-POP-POE block copolymer, a surfactant, and a reflectivity changing reactant, the POE-POP-POE block copolymers solubilizing essentially only non-LDL cholesterol analytes, the non-LDL cholesterol analytes reacting with the reflectivity changing reactant in order to change a reflectivity of the blood sample.

摘要翻译： 在一个实施方案中，用于测试全血中与胆固醇相关的血液分析物的测试条包括红细胞分离层，红细胞分离层，当血液样品流过时将红细胞与施加到测试条的血液样品分离 向下通过红细胞分离层。 测试条还包括从红细胞分离层接收血液样品的反应层，反应层包括POE-POP-POE嵌段共聚物，表面活性剂和反射率变化反应物，POE-POP-POE嵌段共聚物增溶 基本上只有非低密度脂蛋白胆固醇分析物，非低密度脂蛋白胆固醇分析物与反射率变化反应物反应，以改变血样的反射率。

公开(公告)号：US09470698B2

公开(公告)日：2016-10-18

申请号：US14961634

申请日：2015-12-07

申请人： Polymer Technology Systems, Inc.

发明人： Timothy Riley ,  Aniruddha Patwardhan ,  Frank LaDuca

IPC分类号： G01N33/92 ,  G01N21/78 ,  C12Q1/60 ,  G01N33/52 ,  G01N33/48 ,  G01N21/77

CPC分类号： G01N33/92 ,  C12Q1/60 ,  G01N21/78 ,  G01N33/48 ,  G01N33/525 ,  G01N2021/7759 ,  G01N2021/7773

摘要： In one embodiment, a test strip for testing for cholesterol-related blood analytes in whole blood includes a red blood cell separation layer, the red blood cell separation layer separating red blood cells from a blood sample applied to the test strip as the blood sample flows downward through the red blood cell separation layer. The test strip further includes a reaction layer receiving the blood sample from the red blood cell separation layer, the reaction layer including POE-POP-POE block copolymer, a surfactant, and a reflectivity changing reactant, the POE-POP-POE block copolymers solubilizing essentially only non-LDL cholesterol analytes, the non-LDL cholesterol analytes reacting with the reflectivity changing reactant in order to change a reflectivity of the blood sample.

公开(公告)号：US20160084858A1

公开(公告)日：2016-03-24

申请号：US14961634

申请日：2015-12-07

申请人： Polymer Technology Systems, Inc.

发明人： Timothy Riley ,  Aniruddha Patwardhan ,  Frank LaDuca

IPC分类号： G01N33/92 ,  G01N21/78

CPC分类号： G01N33/92 ,  C12Q1/60 ,  G01N21/78 ,  G01N33/48 ,  G01N33/525 ,  G01N2021/7759 ,  G01N2021/7773

摘要： In one embodiment, a test strip for testing for cholesterol-related blood analytes in whole blood includes a red blood cell separation layer, the red blood cell separation layer separating red blood cells from a blood sample applied to the test strip as the blood sample flows downward through the red blood cell separation layer. The test strip further includes a reaction layer receiving the blood sample from the red blood cell separation layer, the reaction layer including POE-POP-POE block copolymer, a surfactant, and a reflectivity changing reactant, the POE-POP-POE block copolymers solubilizing essentially only non-LDL cholesterol analytes, the non-LDL cholesterol analytes reacting with the reflectivity changing reactant in order to change a reflectivity of the blood sample.