公开(公告)号：US20150094285A1

公开(公告)日：2015-04-02

申请号：US14561928

申请日：2014-12-05

申请人： Prachya KONGTAWELERT

发明人： Prachya KONGTAWELERT

IPC分类号： A61K31/36 ,  A23L1/30 ,  A61K45/06

CPC分类号： A61K31/36 ,  A23L33/105 ,  A23V2002/00 ,  A61K45/06 ,  A23V2250/21 ,  A23V2200/324 ,  A23V2200/316

摘要： A composition (e.g., phytochemical composition) including sesamin, the composition exhibiting anti-inflammatory, anti-cytokine storm, connective tissue preservation, anti-viral, and/or other properties in biological tissue. The phytochemical composition therapeutically affects a pro-inflammatory cytokine condition, for instance facilitating or effectuating decrease in a quantity of a pro-inflammatory cytokine, for example, interleukin-1 and tumor necrosis-alpha. The phytochemical composition facilitates or effectuates an increase in quantity of an anti-inflammatory cytokines. The phytochemical composition can additionally facilitate a connective tissue extracellular matrix (ECM) preservation effect. The phytochemical composition can also inhibit an action of a viral neuraminidase, for example, the influenza A virus neuraminidase. Uses of sesamin for manufacture of phytochemical compositions having predetermined concentrations of sesamin include facilitating a decrease in quantity of pro-inflammatory cytokines, an increase in anti-inflammatory cytokines, a connective tissue anti-degenerative effect, and/or an inhibition of viral neuraminidase within the living organism. Manufacturing processes for the phytochemical compositions are also described.

摘要翻译： 包括芝麻素的组合物（例如，植物化学组合物），组合物在生物组织中表现出抗炎，抗细胞因子风暴，结缔组织保存，抗病毒和/或其他性质。 植物化学组成物治疗性地影响促炎细胞因子条件，例如促进或实现促炎细胞因子（例如白细胞介素-1和肿瘤坏死-α）的量的减少。 植物化学成分促进或实现抗炎细胞因子的量的增加。 植物化学成分可另外促进结缔组织细胞外基质（ECM）的保存效果。 植物化学成分也可以抑制病毒性神经氨酸酶，例如甲型流感病毒神经氨酸酶的作用。 用于制造具有预定浓度的芝麻素的植物化学组合物的芝麻素的用途包括促进促炎细胞因子的量的减少，抗炎细胞因子的增加，结缔组织抗退行性作用和/或对病毒神经氨酸酶的抑制 生物体。 还描述了植物化学组合物的制备方法。