公开(公告)号：US20130331399A1

公开(公告)日：2013-12-12

申请号：US13911639

申请日：2013-06-06

Applicant: Psychogenics, Inc.

Inventor： Emer Leahy ,  Bavani Shankar

IPC: A61K31/496 ,  A61K31/198

Abstract: This invention provides methods of treating motor disorder side effects associated with the administration of levodopa to a subject having Parkinson's disease, by administering a dose of eltoprazine or a pharmaceutically acceptable acid addition salt thereof. In particular, the invention provides methods for reducing dyskinesia associated with Parkinson's disease treatments, and effective doses of eltoprazine or a pharmaceutically acceptable acid addition salt thereof.

Abstract translation: 本发明提供了通过施用埃坡替拉嗪或其药学上可接受的酸加成盐来治疗与左旋多巴给予帕金森病患者相关的运动障碍副作用的方法。 特别地，本发明提供了减少与帕金森病治疗相关的运动障碍的方法，以及有效剂量的依托拉嗪或其药学上可接受的酸加成盐。

公开(公告)号：US20180250295A1

公开(公告)日：2018-09-06

申请号：US15971222

申请日：2018-05-04

Applicant: Psychogenics, Inc.

Inventor： Emer Leahy ,  Bavani Shankar

IPC: A61K31/496 ,  A61K31/198

Abstract: This invention provides methods of treating motor disorder side effects associated with the administration of levodopa to a subject having Parkinson's disease, by administering a dose of eltoprazine or a pharmaceutically acceptable acid addition salt thereof. In particular, the invention provides methods for reducing dyskinesia associated with Parkinson's disease treatments, and effective doses of eltoprazine or a pharmaceutically acceptable acid addition salt thereof.