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公开(公告)号:US20060002997A1
公开(公告)日:2006-01-05
申请号:US10525534
申请日:2003-08-25
CPC分类号: A61K9/4808 , A61K9/2027 , A61K9/2054 , A61K9/5084 , A61K31/4178
摘要: The present invention generally relates to controlled release dosage forms which provide immediate release and sustained release of nitrofurantoin, and processes for their preparation. The controlled release dosage form includes a sustained release portion and an immediate release portion. The sustained release portion includes nitrofurantoin and one or more pH dependent hydrophilic polymers. The immediate release portion includes nitrofurantoin.
摘要翻译: 本发明一般涉及提供呋喃妥因立即释放和持续释放的控释剂型及其制备方法。 控释剂型包括持续释放部分和立即释放部分。 持续释放部分包括呋喃妥因和一种或多种pH依赖性亲水性聚合物。 即时释放部分包括呋喃妥因。