公开(公告)号：US20240208971A1

公开(公告)日：2024-06-27

申请号：US18392204

申请日：2023-12-21

Applicant: Purdue Research Foundation

Inventor： Herman O. Sintim ,  Neetu Dayal ,  Clemen Opoku-Temeng

IPC: C07D471/14 ,  C07D209/08 ,  C07D231/56 ,  C07D401/14 ,  C07D413/14 ,  C07D417/12 ,  C07D471/04 ,  C07D491/147 ,  C07D495/14 ,  C07D498/04 ,  C07D513/04 ,  C07D519/00

CPC classification number: C07D471/14 ,  C07D209/08 ,  C07D231/56 ,  C07D401/14 ,  C07D413/14 ,  C07D417/12 ,  C07D471/04 ,  C07D491/147 ,  C07D495/14 ,  C07D498/04 ,  C07D513/04 ,  C07D519/00 ,  C07B2200/05

Abstract: The present invention generally relates to compounds as a dual kinase-demethylase inhibitor useful for the treatment of diseases mediated by a kinase and/or a histone demethylase, such as inflammation, cancer, viral and bacterial infections, neurological and immunological disorders. Pharmaceutical compositions and methods for treating those diseases are within the scope of this invention.