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公开(公告)号:US20210386784A1
公开(公告)日:2021-12-16
申请号:US17412572
申请日:2021-08-26
Applicant: RAMBAM MED-TECH LTD.
Inventor: Igal LOURIA-HAYON , Yishai OFRAN , Michal HAYUN
Abstract: Cells comprising an exogenous protein and decreased SH2B adapter protein 3 (SH2B3) protein expression and/or function are provided. Pharmaceutical compositions comprising the cells of the invention as well as methods of treating a disease in a subject in need thereof comprising administering a cell and/or a pharmaceutical composition of the invention, and of determining suitability for treatment, are also provided.