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公开(公告)号:US20220162595A1
公开(公告)日:2022-05-26
申请号:US17486936
申请日:2021-09-28
Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.
Inventor: Tamir TULLER , Shir BAHIRI , Boaz APT
Abstract: Nucleic acid molecules comprising a mutation that mutation modulates the interaction strength of the nucleic acid molecule to a 16S ribosomal RNA are provided. Methods of improving the translation process of a nucleic acid molecule and producing a nucleic acid molecule optimized for translation, as well as cells comprising the nucleic acid molecules are also provided.