公开(公告)号：US20210108228A1

公开(公告)日：2021-04-15

申请号：US17128736

申请日：2020-12-21

Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.

Inventor： Dan PEER ,  Shiri WEINSTEIN ,  Itai Antoine TOKER ,  Srinivas RAMISHETTI

IPC: C12N15/88 ,  A61K39/395 ,  C07K16/28 ,  A61K47/68 ,  A61K31/7105 ,  A61K31/713 ,  A61K31/105 ,  A61K47/69 ,  A61P35/02 ,  A61K9/00 ,  A61K9/51 ,  A61K48/00

Abstract: Disclosed are targeted lipid based particles for delivery of nucleic acid molecules (such as siRNA) to leukocytes (such as T-Cells and B-cells). Further disclosed are uses of the targeted lipid based particles for treating Leukocytes-associated diseases, such as, cancer.