公开(公告)号：US20240101672A1

公开(公告)日：2024-03-28

申请号：US18482448

申请日：2023-10-06

Applicant: REGENERON PHARMACEUTICALS, INC.

Inventor： Frank KUHNERT ,  Michael VAN METER ,  Thomas NITTOLI

IPC: C07K16/28 ,  A61K47/68 ,  A61P35/02

CPC classification number: C07K16/2809 ,  A61K47/6803 ,  A61K47/6849 ,  A61P35/02

Abstract: The present disclosure provides antibody-drug conjugates comprising anti-PTCRA antibodies and methods of using the same. The ADCs of the disclosure are useful for the treatment of T-ALL and other disorders related to elevated expression of PTCRA.

公开(公告)号：US20210087272A1

公开(公告)日：2021-03-25

申请号：US17026132

申请日：2020-09-18

Applicant: REGENERON PHARMACEUTICALS, INC.

Inventor： Frank KUHNERT ,  Michael VAN METER ,  Thomas NITTOLI

IPC: C07K16/28 ,  A61K47/68 ,  A61P35/02

Abstract: The present disclosure provides antibody-drug conjugates comprising anti-PTCRA antibodies and methods of using the same. The ADCs of the disclosure are useful for the treatment of T-ALL and other disorders related to elevated expression of PTCRA.