公开(公告)号：US20170342143A1

公开(公告)日：2017-11-30

申请号：US15622551

申请日：2017-06-14

Applicant: Rinat Neuroscience Corp.

Inventor： Jaume PONS ,  Arnon ROSENTHAL

IPC: C07K16/22 ,  A61K39/00

CPC classification number: C07K16/22 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2317/24 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/73 ,  C07K2317/76 ,  C07K2317/92

Abstract: The invention concerns anti-NGF antibodies (such as anti-NGF antagonist antibodies), and polynucleotides encoding the same. The invention further concerns use of such antibodies and/or polynucleotides in the treatment and/or prevention of pain, including post-surgical pain, rheumatoid arthritis pain, and osteoarthritis pain.

公开(公告)号：US20130236451A1

公开(公告)日：2013-09-12

申请号：US13767222

申请日：2013-02-14

Applicant: RINAT NEUROSCIENCE CORP.

Inventor： Arnon ROSENTHAL ,  Jaume PONS ,  Wei-Hsien HO

IPC: C07K16/28

CPC classification number: C07K16/18 ,  A61K2039/505 ,  C07K16/28 ,  C07K2317/14 ,  C07K2317/21 ,  C07K2317/41 ,  C07K2317/52 ,  C07K2317/522 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/92

Abstract: Antibodies directed to the C-terminal side of β-amyloid peptide and methods of using these antibodies for diagnosing and treatment of Alzheimer's disease and Aβ peptide associated diseases are described.

Abstract translation: 描述了针对β-淀粉样蛋白肽的C末端侧的抗体以及使用这些抗体诊断和治疗阿尔茨海默病和Aβ肽相关疾病的方法。

公开(公告)号：US20160152698A1

公开(公告)日：2016-06-02

申请号：US14940710

申请日：2015-11-13

Applicant: RINAT NEUROSCIENCE CORP.

Inventor： Jaume PONS ,  Arnon ROSENTHAL

IPC: C07K16/22

CPC classification number: C07K16/22 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2317/24 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/73 ,  C07K2317/76 ,  C07K2317/92

Abstract: The invention concerns anti-NGF antibodies (such as anti-NGF antagonist antibodies), and polynucleotides encoding the same. The invention further concerns use of such antibodies and/or polynucleotides in the treatment and/or prevention of pain, including post-surgical pain, rheumatoid arthritis pain, and osteoarthritis pain.

公开(公告)号：US20160096884A1

公开(公告)日：2016-04-07

申请号：US14966175

申请日：2015-12-11

Applicant: RINAT NEUROSCIENCE CORP.

Inventor： Arnon ROSENTHAL ,  Jaume PONS ,  Wei-Hsien HO

IPC: C07K16/18

CPC classification number: C07K16/18 ,  A61K2039/505 ,  C07K16/28 ,  C07K2317/14 ,  C07K2317/21 ,  C07K2317/41 ,  C07K2317/52 ,  C07K2317/522 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/92

Abstract: Antibodies directed to the C-terminal side of β-amyloid peptide and methods of using these antibodies for diagnosing and treatment of Alzheimer's disease and Aβ peptide associated diseases are described.

Abstract translation: 针对β-淀粉样蛋白肽的C-末端的抗体以及使用这些抗体诊断和治疗阿尔茨海默病和A＆bgr的方法; 描述了肽相关疾病。