公开(公告)号：US20230030564A1

公开(公告)日：2023-02-02

申请号：US17772959

申请日：2020-10-27

Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.

Inventor： Andrea Horsch ,  Eberhard Spanuth

IPC: G01N33/68 ,  G16H50/20 ,  G16H50/30

Abstract: The present invention concerns methods for aiding in the risk assessment of a patient with suspected sepsis. For example, the risk of poor outcome (such as of a complicated clinical course and/or of mortality) can be assessed. The methods of the present invention may comprise the steps of (a) determining the amount of the biomarker Presepsin in a sample from a patient with suspected sepsis who has a known qSOFA (quick Sequential Organ Failure-Assessment) score of 0, 1, 2 or 3, (b) determining the amount of the biomarker Pro-calcitonin (PCT) in a sample from the patient, comparing the amounts determined in steps (b) and (c) to reference amounts, and (d) aiding in the risk assessment of a patient with suspected sepsis. The methods of the present invention may be computer-implemented.