公开(公告)号：US10292994B2

公开(公告)日：2019-05-21

申请号：US14113561

申请日：2012-04-25

申请人： Rakesh Maurya ,  Preety Dixit ,  Ritu Trivedi ,  Vikram Khedgikar ,  Jyoti Gautam ,  Avinash Kumar ,  Divya Singh ,  Shelendra Pratap Singh ,  Wahajuddin ,  Girish Kumar Jain ,  Naibedya Chattopadhyay

发明人： Rakesh Maurya ,  Preety Dixit ,  Ritu Trivedi ,  Vikram Khedgikar ,  Jyoti Gautam ,  Avinash Kumar ,  Divya Singh ,  Shelendra Pratap Singh ,  Wahajuddin ,  Girish Kumar Jain ,  Naibedya Chattopadhyay

IPC分类号： A61K31/7048 ,  C07D311/36 ,  C07H17/07 ,  A61K31/352 ,  A61K36/48

摘要： The present invention relates to bioactive fractions and compounds from Dalbergia sissoo for the prevention or treatment of osteo-health related disorders. The present invention relates in the field of pharmaceutical composition that provides new plant extracts, their fractions and pure compound isolated from natural sources that are useful for the prevention and/or treatment of various medical indications associated with estrogen dependent or independent diseases or syndromes or disorders preferably in the prevention or treatment of estrogen dependent or independent diseases or syndromes or disorders caused in humans and animals, and achievement of peak bone mass during skeletal growth and health in humans and animals. Particularly the present invention further relates to the processes for the preparation of biologically active extracts, fractions, and isolation of pure compounds, from Dalbergia sissoo plant from the family Fabaceae their pharmaceutically acceptable salts and compositions of the principal aspect of the present invention.

公开(公告)号：US20140079834A1

公开(公告)日：2014-03-20

申请号：US14113561

申请日：2012-04-25

申请人： Rakesh Maurya ,  Preety Dixit ,  Ritu Trivedi ,  Vikram Khedgikar ,  Jyoti Gautam ,  Avinash Kumar ,  Divya Singh ,  Sheelendra Pratap Singh ,  (none) Wahajuddin ,  Girish Kumar Jain ,  Naibedya Chattopadhyay

发明人： Rakesh Maurya ,  Preety Dixit ,  Ritu Trivedi ,  Vikram Khedgikar ,  Jyoti Gautam ,  Avinash Kumar ,  Divya Singh ,  Sheelendra Pratap Singh ,  (none) Wahajuddin ,  Girish Kumar Jain ,  Naibedya Chattopadhyay

IPC分类号： A61K31/7048 ,  A61K31/352 ,  A61K36/48

CPC分类号： A61K31/7048 ,  A61K31/352 ,  A61K36/48 ,  C07D311/36 ,  C07H17/07

摘要： The present invention relates to bioactive fractions and compounds from Dalbergia sissoo for the prevention or treatment of osteo-health related disorders. The present invention relates in the field of pharmaceutical composition that provides new plant extracts, their fractions and pure compound isolated from natural sources that are useful for the prevention and/or treatment of various medical indications associated with estrogen dependent or independent diseases or syndromes or disorders preferably in the prevention or treatment of estrogen dependent or independent diseases or syndromes or disorders caused in humans and animals, and achievement of peak bone mass during skeletal growth and health in humans and animals. Particularly the present invention further relates to the processes for the preparation of biologically active extracts, fractions, and isolation of pure compounds, from Dalbergia sissoo plant from the family Fabaceae their pharmaceutically acceptable salts and compositions of the principal aspect of the present invention.

摘要翻译： 本发明涉及用于预防或治疗与骨骼健康相关的疾病的生物活性级分和来自枸杞子的化合物。 本发明涉及药物组合物领域，其提供新的植物提取物，其级分和从天然来源分离的纯化合物，其可用于预防和/或治疗与雌激素依赖性或独立疾病或综合征或病症相关的各种医学适应症 优选地在预防或治疗在人和动物中引起的雌激素依赖性或独立性疾病或综合征或障碍，以及在人和动物的骨骼生长和健康期间达到峰值骨量。 特别地，本发明还涉及从家蚕豆科的Dalbergia sissoo植物制备生物活性提取物，级分和分离纯化合物的方法，它们的药学上可接受的盐和本发明主要方面的组合物。