公开(公告)号：US20200072711A1

公开(公告)日：2020-03-05

申请号：US16554360

申请日：2019-08-28

申请人： Ramot at Tel Aviv University Ltd.

发明人： Micha Fridman ,  Raphael I. Benhamou ,  Ido M. Herzog ,  Qais Z. Jaber

IPC分类号： G01N1/30 ,  G01N33/569 ,  G01N33/58 ,  C09K11/06 ,  C09B62/343

摘要： Particular 1,2,3-triazole- and 1,2,4-triazole-based compounds can be used as fluorescent probes. The compounds can optionally be substituted with one or two fluorine atoms. The compounds are effective as specific endoplasmatic reticulum (ER)-trackers for live cell imaging in a fungal cell, such as a pathogenic yeast. Compositions including the fluorescent probes can be used in methods for tracking the endoplasmic reticulum in a fungal cell.