公开(公告)号：US5124249A

公开(公告)日：1992-06-23

申请号：US442910

申请日：1989-11-28

申请人： Rashid H. Khan ,  Myron R. Szewczuk ,  James H. Day

发明人： Rashid H. Khan ,  Myron R. Szewczuk ,  James H. Day

IPC分类号： C07K16/42 ,  G01N33/68

CPC分类号： C07K16/4241 ,  G01N33/686 ,  Y10S435/965

摘要： Venom immunotherapy is a highly effective treatment for bee sting sensitive individuals. Treated individuals and those naturally exposed to repeated bee stings, such as beekeepers have been shown to develop anti bee venom anti-idiotypic antibodies. These antibodies can be isolated, monoclonal anti-bee venom antibodies can be generated and used in a diagnostic kit to evaluate whether or not an affected individual has developed effective immunity and to evaluate an individual's risk of sensitivity.

摘要翻译： 毒液免疫治疗是对蜂敏感个体的高效治疗。 被治疗的个体和那些自然暴露于重复的蜂蜇的个体，例如养蜂人已被证明发展出抗蜂毒抗独特型抗体。 可以分离这些抗体，可以在诊断试剂盒中产生单克隆抗蜂毒血液抗体，以评估受影响的个体是否发挥了有效的免疫力并评价个体的敏感性风险。