公开(公告)号：US20220268628A1

公开(公告)日：2022-08-25

申请号：US17672959

申请日：2022-02-16

Applicant: Repligen Corporation

Inventor： Rene Daniel Jean-Marie Gantier ,  Mark C. Salerno

IPC: G01J3/42 ,  G01N21/31

Abstract: The present disclosure relates to spectroscopy with light emitting components including, e.g., UV and/or visible wavelength light, for various applications, including, e.g., chromatography, and more particularly, for a sampling device that facilitates spectroscopic measurements with a variable pathlength and methods for such a device. In an aspect, a device for measuring light absorbance of a sample may include a fluid conduit comprising a first portion, a midportion substantially perpendicular to the first portion, and a second portion substantially perpendicular to the midportion. A first probe may be within the midportion and substantially parallel with the midportion. The first probe may comprise a distal end. A light source may be operably coupled to the first probe. A detector may be aligned with the distal end of the first probe substantially perpendicular to the first probe at a pathlength from the distal end of the first probe.