公开(公告)号：US20230256392A1

公开(公告)日：2023-08-17

申请号：US18166520

申请日：2023-02-09

Applicant: Repligen Corporation

Inventor： Mark Perreault ,  Paul Lowell

IPC: B01D61/18 ,  B01D61/14 ,  B01D63/08

CPC classification number: B01D61/18 ,  B01D61/146 ,  B01D63/0822 ,  B01D69/10

Abstract: A self-contained filtration assembly with a self-contained filtration cassette therein. The cassette may be formed from one or more layers membranes and spacers (spacers, screens, or combinations thereof) all having the same general shape. The cassette may have a feed inlet path and a retentate outlet path extending through the layers of the cassette within the perimeter of the cassette, and a permeate outlet path between the cassette exterior and the interior of the cassette housing. The housing may have a generally circular or elliptical cross-section. A clamping assembly may hold together the components of the housing, and may be elongated in a direction along the flow path of the feedstream through the cassette. Various port-defining zones defined in the layers of the cassette may be sealed in a manner facilitating assembly of the cassette as well as isolation of the flow paths therein.