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公开(公告)号:US10696621B2
公开(公告)日:2020-06-30
申请号:US16302618
申请日:2017-02-06
Inventor: Kee Pyung Nahm , Yeon Ji Lee , Bae Geun Lim , Seung A Woo , Ji Inn Oh , Won Gyoung Son
IPC: C07C227/18 , B01J31/02 , C07D471/08 , C07D453/04
Abstract: The present invention relates to a novel chiral phase-transfer catalyst, and a method for preparing an alpha-amino acid by using the same. According to the present invention, an alpha-amino acid of high optical purity could be synthesized in a high yield under an easy industrially applicable reaction condition by using a novel cinchona alkaloid compound as a chiral phase-transfer catalyst, and thus the present invention can be used as a key technique of the asymmetric alpha-amino acid synthesis and preparation field.