公开(公告)号：US09968626B2

公开(公告)日：2018-05-15

申请号：US14827066

申请日：2015-08-14

申请人： Rhamnopharma Inc.

发明人： Anton Leighton

IPC分类号： A01N43/04 ,  A61K31/7028 ,  A61K8/60 ,  A61Q19/06 ,  C07H15/04

CPC分类号： A61K31/7028 ,  A61K8/602 ,  A61Q19/06 ,  C07H15/04

摘要： The present invention is directed to methods for treating obesity, reducing excessive body weight, treating an obesity-related condition, treating unwanted localized fat deposits, and treating areas of cellulite. The method comprises the steps of first identifying a subject in need thereof, and administering to the subject an effective amount of rhamnolipids. A pharmaceutical composition comprising rhamnolipids can be applied by any accepted mode of administration including oral, intranasal, subcutaneous, percutaneous, intravenous, or intracutaneous administration.

公开(公告)号：US09023815B2

公开(公告)日：2015-05-05

申请号：US14088905

申请日：2013-11-25

申请人： Rhamnopharma Inc.

发明人： Anton Leighton

IPC分类号： A61K31/7028 ,  A61K45/06 ,  A61K9/00 ,  A61K31/4174 ,  A61K31/70

CPC分类号： A61K31/7028 ,  A61K9/0043 ,  A61K31/4174 ,  A61K31/70 ,  A61K45/06

摘要： The present invention is directed to methods for treating rhinitis or sinusitis in a subject. In one embodiment, the method comprises the steps of: identifying a subject in need thereof, and administering intranasally to the subject a formulation comprising an only active ingredient of an effective amount of rhamnolipid. In another embodiment, the method comprises the steps of: identifying a subject in need thereof, and administering intranasally to the subject a first active ingredient of an effective amount of a rhamnolipid and a second active ingredient of an effective amount of a corticosteroid, an antihistamine, a leukotriene antagonist, cromylin, an antibiotic, a sphingolipid, or a decongestant.

摘要翻译： 本发明涉及用于治疗受试者鼻炎或鼻窦炎的方法。 在一个实施方案中，所述方法包括以下步骤：鉴定有需要的受试者，以及向所述受试者鼻内施用包含有效量的鼠李糖脂的唯一有效成分的制剂。 在另一个实施方案中，所述方法包括以下步骤：鉴定有需要的受试者，并且向所述受试者鼻内施用有效量的鼠李糖脂的第一活性成分和有效量的皮质类固醇的第二活性成分，抗组胺剂 白细胞三烯拮抗剂，克罗莫林，抗生素，鞘脂或减充血剂。

公开(公告)号：US09107930B2

公开(公告)日：2015-08-18

申请号：US14316652

申请日：2014-06-26

申请人： Rhamnopharma Inc.

发明人： Anton Leighton

IPC分类号： A01N43/04 ,  A61K31/70 ,  A61K31/715 ,  A61K31/7028 ,  A61K8/60 ,  A61Q19/06 ,  C07H15/04

CPC分类号： A61K31/7028 ,  A61K8/602 ,  A61Q19/06 ,  C07H15/04

摘要： The present invention is directed to methods for treating obesity, reducing excessive body weight, treating an obesity-related condition, treating unwanted localized fat deposits, and treating areas of cellulite. The method comprises the steps of first identifying a subject in need thereof, and administering to the subject an effective amount of rhamnolipids. A pharmaceutical composition comprising rhamnolipids can be applied by any accepted mode of administration including oral, intranasal, subcutaneous, percutaneous, intravenous, or intracutaneous administration.

摘要翻译： 本发明涉及治疗肥胖症，减少体重过多，治疗肥胖相关病症，治疗不需要的局部脂肪沉积物以及治疗脂肪团区域的方法。 该方法包括以下步骤：首先鉴定有需要的受试者，并向受试者施用有效量的鼠李糖脂。 包含鼠李糖脂的药物组合物可以通过任何接受的给药方式施用，包括口服，鼻内，皮下，经皮，静脉内或皮内给药。

公开(公告)号：US08765694B2

公开(公告)日：2014-07-01

申请号：US13946931

申请日：2013-07-19

申请人： Rhamnopharma Inc.

发明人： Anton Leighton

IPC分类号： A01N43/04 ,  A61K31/70 ,  A61K31/715

CPC分类号： A61K31/7028 ,  A61K8/602 ,  A61Q19/06 ,  C07H15/04

摘要： The present invention is directed to methods for treating obesity, reducing excessive body weight, treating an obesity-related condition, treating unwanted localized fat deposits, and treating areas of cellulite. The method comprises the steps of first identifying a subject in need thereof, and administering to the subject an effective amount of rhamnolipids. A pharmaceutical composition comprising rhamnolipids can be applied by any accepted mode of administration including oral, intranasal, subcutaneous, percutaneous, intravenous, or intracutaneous administration.

摘要翻译： 本发明涉及治疗肥胖症，减少体重过多，治疗肥胖相关病症，治疗不需要的局部脂肪沉积物以及治疗脂肪团区域的方法。 该方法包括以下步骤：首先鉴定有需要的受试者，并向受试者施用有效量的鼠李糖脂。 包含鼠李糖脂的药物组合物可以通过任何接受的给药方式施用，包括口服，鼻内，皮下，经皮，静脉内或皮内给药。

公开(公告)号：US20140080771A1

公开(公告)日：2014-03-20

申请号：US14088905

申请日：2013-11-25

申请人： Rhamnopharma Inc.

发明人： Anton Leighton

IPC分类号： A61K31/7028 ,  A61K9/00 ,  A61K31/4174 ,  A61K45/06

CPC分类号： A61K31/7028 ,  A61K9/0043 ,  A61K31/4174 ,  A61K31/70 ,  A61K45/06

摘要： The present invention is directed to methods for treating rhinitis or sinusitis in a subject. In one embodiment, the method comprises the steps of: identifying a subject in need thereof, and administering intranasally to the subject a formulation comprising an only active ingredient of an effective amount of rhamnolipid. In another embodiment, the method comprises the steps of: identifying a subject in need thereof, and administering intranasally to the subject a first active ingredient of an effective amount of a rhamnolipid and a second active ingredient of an effective amount of a corticosteroid, an antihistamine, a leukotriene antagonist, cromylin, an antibiotic, a sphingolipid, or a decongestant.

摘要翻译： 本发明涉及用于治疗受试者鼻炎或鼻窦炎的方法。 在一个实施方案中，所述方法包括以下步骤：鉴定有需要的受试者，以及向所述受试者鼻内施用包含有效量的鼠李糖脂的唯一有效成分的制剂。 在另一个实施方案中，所述方法包括以下步骤：鉴定有需要的受试者，并且向所述受试者鼻内施用有效量的鼠李糖脂的第一活性成分和有效量的皮质类固醇的第二活性成分，抗组胺剂 白细胞三烯拮抗剂，克罗莫林，抗生素，鞘脂或减充血剂。