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公开(公告)号：US20100304483A1
公开(公告)日：2010-12-02
申请号：US12796971
申请日：2010-06-09
Applicant: Rivka Abulafia-Lapid , Henri Atlan , Irun R. Cohen
Inventor： Rivka Abulafia-Lapid , Henri Atlan , Irun R. Cohen
IPC: C12N5/0783
CPC classification number: A61K39/0005 , A61K2039/5158 , A61K2039/57 , A61K2039/58
Abstract: A method for the preparation of a T cell vaccine for the treatment of immunodeficient HIV-infected patients is described herein, based on the enrichment of autologous CD4-reactive CD8 T cells. Also described is a protocol for the implementation of T cell vaccination in immunodeficient HIV-infected, as well as a method of treatment, based on the T cell vaccine developed herein. Finally, kits for preparing the T cell vaccine as well as for implementing the protocol are also provided.
Abstract translation: 基于自体CD4反应性CD8T细胞的富集，本文描述了用于制备用于治疗免疫缺陷型HIV感染患者的T细胞疫苗的方法。 还描述了用于在免疫缺陷型HIV感染中实施T细胞疫苗接种的方案，以及基于本文开发的T细胞疫苗的治疗方法。 最后，还提供了用于制备T细胞疫苗以及实施方案的试剂盒。
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公开(公告)号：US07740855B2
公开(公告)日：2010-06-22
申请号：US11290682
申请日：2005-11-30
Applicant: Rivka Abulafia-Lapid , Henri Atlan , Irun R. Cohen
Inventor： Rivka Abulafia-Lapid , Henri Atlan , Irun R. Cohen
IPC: A61K39/00
CPC classification number: A61K39/0005 , A61K2039/5158 , A61K2039/57 , A61K2039/58
Abstract: A method for the preparation of a T cell vaccine for the treatment of immunodeficient HIV-infected patients is described herein, based on the enrichment of autologous CD4-reactive CD8 T cells. Also described is a protocol for the implementation of T cell vaccination in immunodeficient HIV-infected, as well as a method of treatment, based on the T cell vaccine developed herein. Finally, kits for preparing the T cell vaccine as well as for implementing the protocol are also provided.
Abstract translation: 基于自体CD4反应性CD8T细胞的富集，本文描述了用于制备用于治疗免疫缺陷型HIV感染患者的T细胞疫苗的方法。 还描述了用于在免疫缺陷型HIV感染中实施T细胞疫苗接种的方案，以及基于本文开发的T细胞疫苗的治疗方法。 最后，还提供了用于制备T细胞疫苗以及实施方案的试剂盒。
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公开(公告)号：US20070122877A1
公开(公告)日：2007-05-31
申请号：US11290682
申请日：2005-11-30
Applicant: Rivka Abulafia-Lapid , Henri Atlan , Irun Cohen
Inventor： Rivka Abulafia-Lapid , Henri Atlan , Irun Cohen
CPC classification number: A61K39/0005 , A61K2039/5158 , A61K2039/57 , A61K2039/58
Abstract: A method for the preparation of a T cell vaccine for the treatment of immunodeficient HIV-infected patients is described herein, based on the enrichment of autologous CD4-reactive CD8 T cells. Also described is a protocol for the implementation of T cell vaccination in immunodeficient HIV-infected, as well as a method of treatment, based on the T cell vaccine developed herein. Finally, kits for preparing the T cell vaccine as well as for implementing the protocol are also provided.
Abstract translation: 基于自体CD4反应性CD8T细胞的富集，本文描述了用于制备用于治疗免疫缺陷型HIV感染患者的T细胞疫苗的方法。 还描述了用于在免疫缺陷型HIV感染中实施T细胞疫苗接种的方案，以及基于本文开发的T细胞疫苗的治疗方法。 最后，还提供了用于制备T细胞疫苗以及实施方案的试剂盒。
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