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    Device and method for treatment of gastroesophageal reflux disease
    6.
    发明授权
    Device and method for treatment of gastroesophageal reflux disease 有权
    用于治疗胃食管反流病的装置和方法

    公开(公告)号：US07400929B2

    公开(公告)日：2008-07-15

    申请号：US11279025

    申请日：2006-04-07

    申请人： Brian D. Zelickson ,  Robert A. Ganz

    发明人： Brian D. Zelickson ,  Robert A. Ganz

    IPC分类号： A61B18/18

    CPC分类号： A61B18/1815 ,  A61B1/00082 ,  A61B1/018 ,  A61B18/08 ,  A61B18/1492 ,  A61B18/20 ,  A61B2018/00011 ,  A61B2018/00214 ,  A61B2018/00553

    摘要： A lower esophageal sphincter tightening device for treating gastroesophageal reflux disease which includes an insertion device, an energy source, and an energy transmitting device. The insertion device, by insertion through a body opening, positions the energy transmitting device in the proximity of the lower esophageal sphincter. The energy source generates and transmits energy via the insertion device to the energy transmitting device which directs the transmitted energy onto the lower esophageal sphincter which is comprised largely of collagen. The energy source transmits energy at a level sufficient to cause heating of the sphincter's collagen resulting in a shrinkage of the collagen and a tightening of the sphincter.

    摘要翻译： 一种用于治疗胃食管反流病的下食道括约肌紧固装置，其包括插入装置，能量源和能量传递装置。 插入装置通过插入体开口将能量传递装置定位在食管下括约肌附近。 能量源通过插入装置产生能量并将能量传递到能量传递装置，该能量传递装置将传播的能量引导到主要由胶原蛋白组成的下部食管括约肌上。 能量源以足以引起括约肌胶原加热的水平传输能量，从而导致胶原蛋白的收缩和括约肌紧缩。

    Device and method for treatment of gastroesophageal reflux disease
    7.
    发明授权
    Device and method for treatment of gastroesophageal reflux disease 失效
    用于治疗胃食管反流病的装置和方法

    公开(公告)号：US07761169B2

    公开(公告)日：2010-07-20

    申请号：US12136730

    申请日：2008-06-10

    申请人： Brian D. Zelickson ,  Robert A. Ganz

    发明人： Brian D. Zelickson ,  Robert A. Ganz

    IPC分类号： A61B18/18

    CPC分类号： A61B18/1815 ,  A61B1/00082 ,  A61B1/018 ,  A61B18/08 ,  A61B18/1492 ,  A61B18/20 ,  A61B2018/00011 ,  A61B2018/00214 ,  A61B2018/00553

    摘要： A lower esophageal sphincter tightening device for treating gastroesophageal reflux disease which includes an insertion device, an energy source, and an energy transmitting device. The insertion device, by insertion through a body opening, positions the energy transmitting device in the proximity of the lower esophageal sphincter. The energy source generates and transmits energy via the insertion device to the energy transmitting device which directs the transmitted energy onto the lower esophageal sphincter which is comprised largely of collagen. The energy source transmits energy at a level sufficient to cause heating of the sphincter's collagen resulting in a shrinkage of the collagen and a tightening of the sphincter.

    摘要翻译： 一种用于治疗胃食管反流病的下食道括约肌紧固装置，其包括插入装置，能量源和能量传递装置。 插入装置通过插入体开口将能量传递装置定位在食管下括约肌附近。 能量源通过插入装置产生能量并将能量传递到能量传递装置，该能量传递装置将传播的能量引导到主要由胶原蛋白组成的下部食管括约肌上。 能量源以足以引起括约肌胶原加热的水平传输能量，从而导致胶原蛋白的收缩和括约肌紧缩。

    Device and method for treatment of gastroesophageal reflux disease
    9.
    发明授权
    Device and method for treatment of gastroesophageal reflux disease 有权
    用于治疗胃食管反流病的装置和方法

    公开(公告)号：US06321121B1

    公开(公告)日：2001-11-20

    申请号：US09475580

    申请日：1999-12-30

    申请人： Brian D. Zelickson ,  Robert A. Ganz

    发明人： Brian D. Zelickson ,  Robert A. Ganz

    IPC分类号： A61F200

    CPC分类号： A61B18/1815 ,  A61B1/00082 ,  A61B1/018 ,  A61B18/08 ,  A61B18/1492 ,  A61B18/20 ,  A61B2018/00011 ,  A61B2018/00214 ,  A61B2018/00553

    摘要： A lower esophageal sphincter tightening device for treating gastroesophageal reflux disease which includes an insertion device, an energy source, and an energy transmitting device. The insertion device, by insertion through a body opening, positions the energy transmitting device in the proximity of the lower esophageal sphincter. The energy source generates and transmits energy via the insertion device to the energy transmitting device which directs the transmitted energy onto the lower esophageal sphincter which is comprised largely of collagen. The energy source transmits energy at a level sufficient to cause heating of the sphincter's collagen resulting in a shrinkage of the collagen and a tightening of the sphincter.

    摘要翻译： 一种用于治疗胃食管反流病的下食道括约肌紧固装置，其包括插入装置，能量源和能量传递装置。 插入装置通过插入体开口将能量传递装置定位在食管下括约肌附近。 能量源通过插入装置产生能量并将能量传递到能量传递装置，该能量传递装置将传播的能量引导到主要由胶原蛋白组成的下部食管括约肌上。 能量源以足以引起括约肌胶原加热的水平传输能量，从而导致胶原蛋白的收缩和括约肌紧缩。

    Device and method for treatment of gastroesophageal reflux disease
    10.
    发明授权
    Device and method for treatment of gastroesophageal reflux disease 有权
    用于治疗胃食管反流病的装置和方法

    公开(公告)号：US07933659B2

    公开(公告)日：2011-04-26

    申请号：US12839112

    申请日：2010-07-19

    申请人： Brian D. Zelickson ,  Robert A. Ganz

    发明人： Brian D. Zelickson ,  Robert A. Ganz

    IPC分类号： A61B12/00 ,  A61B18/18

    CPC分类号： A61B18/1815 ,  A61B1/00082 ,  A61B1/018 ,  A61B18/08 ,  A61B18/1492 ,  A61B18/20 ,  A61B2018/00011 ,  A61B2018/00214 ,  A61B2018/00553

    摘要： A lower esophageal sphincter tightening device for treating gastroesophageal reflux disease which includes an insertion device, an energy source, and an energy transmitting device. The insertion device, by insertion through a body opening, positions the energy transmitting device in the proximity of the lower esophageal sphincter. The energy source generates and transmits energy via the insertion device to the energy transmitting device which directs the transmitted energy onto the lower esophageal sphincter which is comprised largely of collagen. The energy source transmits energy at a level sufficient to cause heating of the sphincter's collagen resulting in a shrinkage of the collagen and a tightening of the sphincter.

    摘要翻译： 一种用于治疗胃食管反流病的下食道括约肌紧固装置，其包括插入装置，能量源和能量传递装置。 插入装置通过插入体开口将能量传递装置定位在食管下括约肌附近。 能量源通过插入装置产生能量并将能量传递到能量传递装置，该能量传递装置将传播的能量引导到主要由胶原蛋白组成的下部食管括约肌上。 能量源以足以引起括约肌胶原加热的水平传输能量，从而导致胶原蛋白的收缩和括约肌紧缩。