-
公开(公告)号:US5958426A
公开(公告)日:1999-09-28
申请号:US824646
申请日:1997-03-24
IPC分类号: C12P13/00 , A01N33/08 , A01N37/20 , A01N49/00 , A01N57/12 , A61K31/66 , A61K45/00 , A61P3/08 , A61P3/10 , A61P29/00 , A61P35/00 , A61P43/00 , C07F9/09 , C07F9/113 , C12P13/02 , C12R1/645
CPC分类号: A61K31/661 , A01N33/08 , A01N37/20 , A01N49/00 , A01N57/12 , A61K45/00 , C07F9/091 , C07F9/113 , C12P13/02
摘要: A process for novel sphingolipids and other secondary sphingosine-based compounds is provided which comprises the culturing of an appropriate fungus, harvesting mycelium from the fungus and isolating the sphingolipid from the mycelium. The sphingosine-based materials inhibit protein kinase C, provide an anti-inflammatory effect or provide an anti-tumor effect; furthermore, these sphingosine-based materials provide protection for plants against pathogenic microorganisms.
摘要翻译: 提供新型鞘脂和其它次级鞘氨醇类化合物的方法,其包括培养合适的真菌,从真菌中收获菌丝体并从菌丝体中分离鞘脂。 基于鞘氨醇的物质抑制蛋白激酶C,提供抗炎作用或提供抗肿瘤作用; 此外,这些基于鞘氨醇的材料为防止病原微生物的植物提供保护。