专利检索 ap:("Robert Bucourt" OR "Alain Piasco" OR "Claude Tchernatinsky") AND inv:"Alain Piasco" 第 1 页

1.

发明授权
3-keto-nor-pregnenes substituted in the 6-position and treatment of menopause 失效
标题翻译：在6-位取代的3-酮 - 去甲孕烯和治疗更年期

公开(公告)号：US5795884A

公开(公告)日：1998-08-18

申请号：US643623

申请日：1996-05-06

申请人： Robert Bucourt , Alain Piasco , Claude Tchernatinsky

发明人： Robert Bucourt , Alain Piasco , Claude Tchernatinsky

IPC分类号： C07J7/00 , A61K31/56 , C07J5/00

CPC分类号： C07J7/0045

摘要： A 3-keto-19-nor-pregnene of the formula ##STR1## wherein R is selected from the group consisting of hydroxy, acyloxy of an organic carboxylic acid, lower alkoxy, halogen and lower alkyl, R' is selected from the group consisting of hydrogen and halogen, or R and R' together form oxygen, R.sub.3 is selected from the group consisting of methyl, --OH and lower acyloxy of an organic carboxylic acid and the dotted line is an optional double bond in the 6,7-position useful for treating the symptoms of menopause in females.

摘要翻译： 其中R选自羟基，有机羧酸的酰氧基，低级烷氧基，卤素和低级烷基，R'选自下组的3-酮-19-去甲孕烯烯，其中R选自：的氢和卤素，或R和R'一起形成氧，R 3选自有机羧酸的甲基，-OH和低级酰氧基，虚线是6,7位任选的双键可用于治疗女性更年期症状。

2.

发明授权
19-nor-pregnene derivatives and pharmaceuticals containing such derivatives 失效
标题翻译：含有该衍生物的19-去甲孕烯衍生物和药物

公开(公告)号：US06180803B2

公开(公告)日：2001-01-30

申请号：US09101775

申请日：1998-11-05

申请人： Alain Piasco , Jean Lafay , R{acute over (e)}mi Delansorne , Jacques Paris , Jean-Claude Pascal

发明人： Alain Piasco , Jean Lafay , R{acute over (e)}mi Delansorne , Jacques Paris , Jean-Claude Pascal

IPC分类号： C07J4100

CPC分类号： C07J7/0045 , C07J21/006 , C07J41/0016 , C07J53/004 , C07J71/001

摘要： The invention relates to compounds of the formula: in which R1, R2, R3, R4, R5, R6, n and X are as defined in the specification, and to pharmaceutical compositions containing them. These compounds are excellent progestogens which are devoid of residual androgenic activity.

摘要翻译： 本发明涉及下式的化合物：其中R 1，R 2，R 3，R 4，R 5，R 6，n和X如说明书中所定义，以及含有它们的药物组合物。这些化合物是没有残留的优异的孕激素雄激素活性。

3.

发明授权
Derivatives of 19-nor progesterone; process for producing them and the pharmaceutical compositions incorporating them 失效
标题翻译： 19-没有孕酮的衍生物生产它们的方法和包含它们的药物组合物

公开(公告)号：US5223492A

公开(公告)日：1993-06-29

申请号：US749925

申请日：1991-08-26

申请人： Nejib M. Nasraoui , Alain Piasco

发明人： Nejib M. Nasraoui , Alain Piasco

IPC分类号： C07J9/00 , C07J13/00

CPC分类号： C07J9/00 , C07J13/007

摘要： This invention relates to the field of chemistry and more precisely to the field of medicinal Chemistry.It has specifically as subject matter the compounds of general formula I ##STR1## wherein R is a hydrogen, a lower alkyl radical a methoxymethyl, a tetrahydropyranyl or the acyl residue of an organic carboxylic.

摘要翻译： 本发明涉及化学领域，更具体地涉及药物化学领域。具体地说，作为主题，通式I的化合物（I）其中R是氢，低级烷基，甲氧基甲基，四氢吡喃基或有机羧酸的酰基残基。