专利检索 ap:("Rodney L. Parsons" OR "Roberta L. Dorow" OR "Akin H. Davulcu" OR "Joseph M. Fortunak" OR "Gregory D. Harris" OR "Goss S. Kauffman" OR "William A. Nugent" OR "Lilian A. Radesca") AND inv:"Rodney L. Parsons" 第 1 页

1.

发明授权
Asymmetric synthesis of quinazolin-2-ones useful as HIV reverse transcriptase inhibitors 失效

公开(公告)号：US06555686B2

公开(公告)日：2003-04-29

申请号：US09909731

申请日：2001-07-20

申请人： Rodney L. Parsons , Roberta L. Dorow , Akin H. Davulcu , Joseph M. Fortunak , Gregory D. Harris , Goss S. Kauffman , William A. Nugent , Lilian A. Radesca

发明人： Rodney L. Parsons , Roberta L. Dorow , Akin H. Davulcu , Joseph M. Fortunak , Gregory D. Harris , Goss S. Kauffman , William A. Nugent , Lilian A. Radesca

IPC分类号： C07D23972

CPC分类号： C07D239/80

摘要： This invention relates generally to the asymmetric synthesis of quinazolin-2-ones that are useful as inhibitors of HIV reverse transcriptase. The synthesis is accomplished through the chiral ligand mediated addition of cyclopropylacetylide.