-
公开(公告)号:US06541002B1
公开(公告)日:2003-04-01
申请号:US09281495
申请日:1999-03-30
IPC分类号: A61K3900
CPC分类号: C07K7/08 , A61K38/00 , C07K1/047 , C07K5/1008 , C07K5/1016 , C07K7/06 , C07K2319/00 , C12N2799/027
摘要: Compositions and methods for rendering a polypeptide capable of binding with Vpr and to susceptible to incorporation into a are provided. Methods of treating a human patient infected with a virus which expresses Vpr and methods of providing a polypeptide to a cell of a human patient are also included. The invention further includes a method of determining whether a polypeptide comprises a Vpr-binding region.
摘要翻译: 提供了使能够与Vpr结合并易于掺入的多肽的组合物和方法。 还包括用于治疗感染了表达Vpr的病毒的人类患者的方法和向人类患者的细胞提供多肽的方法。 本发明还包括确定多肽是否包含Vpr结合区的方法。