公开(公告)号：US06737543B2

公开(公告)日：2004-05-18

申请号：US10083631

申请日：2002-02-26

申请人： Ronald J. Smith ,  Maria K. Smith ,  Sayer B. Needelman ,  G. Frank DeMonico

发明人： Ronald J. Smith ,  Maria K. Smith ,  Sayer B. Needelman ,  G. Frank DeMonico

IPC分类号： C07C6902

CPC分类号： C07C69/24 ,  A61K8/27 ,  A61K8/29 ,  A61K8/39 ,  A61Q17/04

摘要： A novel fatty polypropoxylate ester which is an ester of an aliphatic or an aromatic monoacid formed by reacting the acid with a stoichiometric excess of a polypropoxylated fatty alcohol. The compounds have the following structural formula: wherein R1 is a polypropoxylated fatty alcohol having the structural formula: wherein R5 is a saturated or unsaturated, substituted or unsubstituted aliphatic or aromatic moiety containing from 4 to 24 carbon atoms, and x is an integer from 3 to 30; and wherein R has the structural formula: wherein R2, R3 and R4 are independently selected from the group consisting of methyl, ethyl, propyl or isopropyl; or wherein R6 is H or OH or NH2 or methyl or ethyl. The compounds possess exceptional pigment dispersant and esthetic emollient properties for use in personal care and topical pharmaceutical preparations, e.g., lipsticks, cream foundations, waterproof sunscreens, sunscreen lotions.

摘要翻译： 一种新型脂肪聚丙酸酯，其是通过酸与化学计量过量的聚丙氧基化脂肪醇反应形成的脂肪族或芳族一元酸的酯。 所述化合物具有以下结构式：其中R1是具有以下结构式的聚丙氧基化脂肪醇：其中R5是含有4至24个碳原子的饱和或不饱和的，取代或未取代的脂族或芳族部分，x是3的整数 至30 其中R具有以下结构式：其中R2，R3和R4独立地选自甲基，乙基，丙基或异丙​​基; 或其中R 6为H或OH或NH 2或甲基或乙基。该化合物具有卓越的颜料分散剂和美学润肤剂性质，用于个人护理和局部药物制剂，例如唇膏，霜基，防水防晒霜，防晒乳液。