公开(公告)号：US09708303B2

公开(公告)日：2017-07-18

申请号：US14747745

申请日：2015-06-23

申请人： SARcode Bioscience Inc.

发明人： James Robert Zeller ,  Sripathy Venkatraman ,  Elisabeth C. A. Brot ,  Subashree Iyer ,  Michael Hall

IPC分类号： C07D405/06 ,  C07D407/06

CPC分类号： C07D407/06 ,  C07B2200/13 ,  C07D405/06

摘要： Methods of preparation and purification of a compound of Formula I, intermediates thereof, a polymorph thereof, and related compounds are disclosed. Formulations and uses thereof in the treatment of LFA-1 mediated diseases are also disclosed.

公开(公告)号：US10214517B2

公开(公告)日：2019-02-26

申请号：US15621141

申请日：2017-06-13

申请人： SARcode Bioscience Inc.

发明人： James Robert Zeller ,  Sripathy Venkatraman ,  Elisabeth C. A. Brot ,  Subashree Iyer ,  Michael Hall

IPC分类号： C07D405/06 ,  C07D407/06

摘要： Methods of preparation and purification of a compound of Formula I, intermediates thereof, a polymorph thereof, and related compounds are disclosed. Formulations and uses thereof in the treatment of LFA-1 mediated diseases are also disclosed.

公开(公告)号：US09085553B2

公开(公告)日：2015-07-21

申请号：US13950807

申请日：2013-07-25

申请人： SARcode Bioscience Inc.

发明人： James Robert Zeller ,  Sripathy Venkatraman ,  Elisabeth C. A. Brot ,  Subashree Iyer ,  Michael Hall

IPC分类号： C07D405/06

CPC分类号： C07D407/06 ,  C07B2200/13 ,  C07D405/06

摘要： Methods of preparation and purification of a compound of Formula I, intermediates thereof, a polymorph thereof, and related compounds are disclosed. Formulations and uses thereof in the treatment of LFA-1 mediated diseases are also disclosed.

摘要翻译： 公开了制备和纯化式I化合物的方法，其中间体，其多晶型物和相关化合物。 还公开了其在治疗LFA-1介导的疾病中的制剂及其用途。

公开(公告)号：US20140031387A1

公开(公告)日：2014-01-30

申请号：US13950807

申请日：2013-07-25

申请人： SARcode Bioscience Inc.

发明人： James Robert Zeller ,  Sripathy Venkatraman ,  Elisabeth C. A. Brot ,  Subashree Iyer ,  Michael Hall

IPC分类号： C07D405/06

CPC分类号： C07D407/06 ,  C07B2200/13 ,  C07D405/06

摘要： Methods of preparation and purification of a compound of Formula I, intermediates thereof, a polymorph thereof, and related compounds are disclosed. Formulations and uses thereof in the treatment of LFA-1 mediated diseases are also disclosed.

摘要翻译： 公开了制备和纯化式I化合物的方法，其中间体，其多晶型物和相关化合物。 还公开了其在治疗LFA-1介导的疾病中的制剂及其用途。