公开(公告)号：US20230365584A1

公开(公告)日：2023-11-16

申请号：US18025465

申请日：2021-09-08

Applicant: SCHRÖDINGER, INC.

Inventor： Xianhai HUANG ,  Sayan MONDAL ,  Phani GHANAKOTA ,  Nicholas BOYLES ,  Leah FRYE ,  Adam LEVINSON ,  Jeremy Robert GREENWOOD ,  Pieter BOS ,  Sathesh BHAT ,  Aleksey GERASYUTO ,  Haifeng TANG

IPC: C07D495/16 ,  A61K45/06

CPC classification number: C07D495/16 ,  A61K45/06

Abstract: The present application relates to compounds of Formula (I), as defined herein, and pharmaceutically acceptable salts thereof. The present application also describes pharmaceutical composition comprising a compound of Formula (I), and pharmaceutically acceptable salts thereof, and methods of using the compounds and compositions for inhibiting kinase activity, and for treating cancer.

公开(公告)号：US20240199634A1

公开(公告)日：2024-06-20

申请号：US18282318

申请日：2022-03-17

Applicant: SCHRÖDINGER, INC.

Inventor： Sayan MONDAL ,  Haifeng TANG ,  Xianhai HUANG ,  Adam Marc LEVINSON ,  Leah FRYE ,  Sathesh BHAT ,  Pieter Harm BOS ,  Zef KONST ,  Phani GHANAKOTA ,  Jeremy Robert GREENWOOD

IPC: C07D495/04 ,  A61K31/4365 ,  A61K31/4375 ,  A61K31/4743 ,  A61K31/5377 ,  C07D495/14

CPC classification number: C07D495/04 ,  A61K31/4365 ,  A61K31/4375 ,  A61K31/4743 ,  A61K31/5377 ,  C07D495/14

Abstract: The present application relates to compounds of Formula (I), as defined herein, and pharmaceutically acceptable salts thereof. The present application also describes pharmaceutical composition comprising a compound of Formula (I), and pharmaceutically acceptable salts thereof, and methods of using the compounds and compositions for inhibiting kinase activity, and for treating cancer.