专利检索 ap:("SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION" OR "EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION") AND inv:"SI WON HWANG" 第 1 页

1.

发明公开
ANTI CD154 ANTIBODY AND USE THEREOF 审中-公开

公开(公告)号：US20240336690A1

公开(公告)日：2024-10-10

申请号：US18293425

申请日：2022-08-01

申请人： SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION , EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION

发明人： JUN HO CHUNG , KYUNG HO CHOI , SANG IL KIM , YOUNG JAE LEE , SU JEONG KIM , SEO RYEONG PARK , SI WON HWANG , DONG MIN KANG , SU REE KIM

IPC分类号： C07K16/28 , A61K47/68

CPC分类号： C07K16/2875 , A61K47/6803 , A61K47/68031 , A61K47/6849 , C07K2317/622 , C07K2317/76

摘要： An antibody binds to CD154. The antibody includes HCDR, which includes amino acid sequences of SEQ ID NOs: 1 to 3, and LCDR which includes amino acid sequences of SEQ ID NOs: 4 to 6. A composition including an antibody-drug conjugate in which a drug is conjugated to the antibody may prevent or treat a T cell-mediated autoimmune disease and/or organ transplant rejection.