公开(公告)号：US20030036500A1

公开(公告)日：2003-02-20

申请号：US10233580

申请日：2002-09-04

Applicant: SEPRACOR, INC.

Inventor： Paul D. Rubin ,  Timothy Barberich

IPC: A61K031/00

CPC classification number: A61K31/135 ,  A61K31/415 ,  A61K31/445 ,  A61K38/16 ,  A61K45/06 ,  A61K2300/00

Abstract: The invention relates to methods and compositions for the prevention, treatment, or management of gastrointestinal disorders or symptoms thereof, employing two or more agents or compounds to provide a triple site action on 5-HT3 receptors, 5-HT4 receptors, and at least one of H2 receptors and proton pumps.