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公开(公告)号:US20120005776A1
公开(公告)日:2012-01-05
申请号:US13171751
申请日:2011-06-29
申请人: SHAHARYAR KHAN
发明人: SHAHARYAR KHAN
CPC分类号: C12N15/8202 , A61K48/005 , A61K48/0058 , C07K2319/07 , C07K2319/09 , C07K2319/10 , C07K2319/81 , C12N15/62 , C12N15/85
摘要: Methods and compositions for delivering polynucleotides are provided. One embodiment provides a non-viral vector comprising a recombinant polynucleotide-binding protein comprising a protein transduction domain operably linked to a targeting signal. Methods for modifying the genome of non-nuclear organelles are also provided.
摘要翻译: 提供了用于递送多核苷酸的方法和组合物。 一个实施方案提供了包含重组多核苷酸结合蛋白的非病毒载体,所述重组多核苷酸结合蛋白包含与靶向信号可操作地连接的蛋白转 还提供了修饰非核细胞器基因组的方法。