公开(公告)号：US20240270753A1

公开(公告)日：2024-08-15

申请号：US18560605

申请日：2022-03-30

Applicant: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

Inventor： Bing ZHOU ,  Jia LI ,  Yubo ZHOU ,  Xiangbo YANG ,  Bo FENG ,  Yaxi YANG ,  Xiaobei HU

IPC: C07D491/107 ,  A61K31/497 ,  A61K31/5025 ,  C07D519/00

CPC classification number: C07D491/107 ,  A61K31/497 ,  A61K31/5025 ,  C07D519/00

Abstract: The present invention relates to a heterocyclic compound for inhibiting SHP2 activity that is represented by formula I, a preparation method therefor and use thereof. The compound of the present invention is effective in treating a disease or disorder or condition mediated by SHP2.