专利检索 ap:("SHANGHAI ZHEYE BIOTECHNOLOGY LIMITED-LIABILITY COMPANY") AND inv:"Jianyu Liu" 第 1 页

1.

发明授权
Compound for selectively inhibiting kinase and use thereof 有权

公开(公告)号：US11046684B2

公开(公告)日：2021-06-29

申请号：US16474991

申请日：2017-12-29

申请人： SHANGHAI ZHEYE BIOTECHNOLOGY LIMITED-LIABILITY COMPANY

发明人： Jianyu Liu , Haidong Zhang

IPC分类号： C07D471/04 , A61P35/00

摘要： Provided are a compound of formula (I), a stereoisomer, a tautomer or a pharmaceutically acceptable salt thereof, use thereof as a selective inhibitor for FGFR4 kinase and use thereof in manufacturing a medicament or pharmaceutical composition for treating diseases due to FGFR4 or FGF19. The compound disclosed by the invention has selective and significant inhibitory activities against FGFR4, and has wide application prospect in the field of tumor treatment.