专利检索 ap:("SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD.") AND inv:"Wanqiu Wang" 第 1 页

1.

发明授权
Vinylarene derivative and application 有权

公开(公告)号：US11370762B2

公开(公告)日：2022-06-28

申请号：US16489815

申请日：2018-05-31

申请人： SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD.

发明人： Zhaojin Ran , Baoshan Chai , Wanqiu Wang , Haihong Guang , Jiayuan Jiao

IPC分类号： A61P35/00 , C07D257/04 , C07C233/55 , C07C275/40 , C07C275/42 , C07C335/22

摘要： The present invention relates to a vinylarene deriv. which modulates or inhibits the enzymic activity of indoleamine 2,3-dioxygenase 1 (IDO-1), and the use thereof, and further relates to a vinylarene deriv. and the use thereof. The vinylarene deriv. and its stereoisomer, cis- or trans-isomer, or tautomer thereof and pharmaceutically acceptable salt thereof, has an IDO-1 enzyme inhibitory activity, and is expected to provide brand new therapeutic methods and schemes for related diseases caused by IDO enzymes.