公开(公告)号：US20030134264A1

公开(公告)日：2003-07-17

申请号：US10162738

申请日：2002-06-06

Applicant: SHISEIDO COMPANY, LTD.

Inventor： Kazuhisa Maeda ,  Masato Hatao

IPC: C12Q001/00 ,  A61K007/42 ,  A61K031/375

CPC classification number: A61Q17/04 ,  A61K8/492 ,  A61K8/676 ,  A61Q19/02

Abstract: A method of preventing darkening of the skin or inhibiting melanization caused by the irradiation of the melanin monomers with long wavelength ultraviolet rays having a wavelength of 320-400 nm as well as a polymerization inhibitor of a biological dihydroxyindole compound comprising 3-O-ethyl ascorbic acid and an external skin treatment composition containing the same.

Abstract translation: 防止由波长320-400nm的长波长紫外线照射黑色素单体引起的皮肤变黑或抑制黑色素化的方法，以及包含抗坏血酸3-O-乙酸的生物二羟基吲哚化合物的阻聚剂 酸和含有其的外用皮肤治疗组合物。