公开(公告)号：US20220402902A1

公开(公告)日：2022-12-22

申请号：US17378957

申请日：2021-07-19

Applicant: SK BIOPHARMACEUTICALS CO., LTD.

Inventor： Yong Je SHIN ,  Jin Hee KIM ,  Jun LEE ,  Sook Kyung PARK ,  Ho Yeon LEE ,  Hyun Suk CHOI ,  Se Hyuk KIM ,  Eun Ji KANG ,  Ho Youl LEE ,  Soo Yeon JUNG

IPC: C07D413/06 ,  C07D413/14 ,  C07D491/08 ,  C07D491/107 ,  C07D401/06

Abstract: The present disclosure relates to a compound derivative containing a 6-7 bicyclic ring and use thereof. The compound according to the present invention can be effectively used in the prevention or treatment of diseases caused by PRMT5 by acting as a PRMT5 inhibitor.

公开(公告)号：US20230023140A1

公开(公告)日：2023-01-26

申请号：US17771114

申请日：2020-10-22

Applicant: SK BIOPHARMACEUTICALS CO., LTD.

Inventor： Yong Je SHIN ,  Jin Hee KIM ,  Jun LEE ,  Hyun Suk CHOI ,  Se Hyuk KIM ,  Eun Ji KANG ,  Sook Kyung PARK ,  Ho Youl LEE ,  Ho Yeon LEE

IPC: C07D401/14 ,  C07D401/06 ,  C07D405/14 ,  C07D491/107 ,  C07D413/14 ,  C07D417/14 ,  C07D471/08 ,  C07D491/08 ,  C07D471/04 ,  C07D498/04 ,  A61P35/00

Abstract: The present invention relates to a 6-6 bicyclic ring-containing compound derivative and use thereof. The compound according to the present invention acts as a PRMT5 inhibitor, and thus can be effectively used in the prevention or treatment of diseases caused by PRMT5.

公开(公告)号：US20230286965A1

公开(公告)日：2023-09-14

申请号：US18122780

申请日：2023-03-17

Applicant: SK BIOPHARMACEUTICALS CO., LTD.

Inventor： Yong Je SHIN ,  Jin Hee KIM ,  Jun LEE ,  Sook Kyung PARK ,  Ho Yeon LEE ,  Hyun Suk CHOI ,  Se Hyuk KIM ,  Eun Ji KANG ,  Ho Youl LEE ,  Soo Yeon JUNG

IPC: C07D413/06 ,  C07D401/06 ,  C07D413/14 ,  C07D491/107 ,  C07D401/14 ,  C07D405/14 ,  C07D491/08 ,  C07D487/04 ,  A61P35/00

CPC classification number: C07D413/06 ,  A61P35/00 ,  C07D401/06 ,  C07D401/14 ,  C07D405/14 ,  C07D413/14 ,  C07D487/04 ,  C07D491/08 ,  C07D491/107

Abstract: The present disclosure relates to a compound derivative containing a 6-7 bicyclic ring and use thereof. The compound according to the present disclosure can be effectively used in the prevention or treatment of diseases caused by PRMT5 by acting as a PRMT5 inhibitor.

公开(公告)号：US20240051951A1

公开(公告)日：2024-02-15

申请号：US18207401

申请日：2023-06-08

Applicant: SK BIOPHARMACEUTICALS CO., LTD.

Inventor： Yong Je SHIN ,  Jin Hee KIM ,  Jun LEE ,  Sook Kyung PARK ,  Ho Yeon LEE ,  Hyun Suk CHOI ,  Se Hyuk KIM ,  Eun Ji KANG ,  Ho Youl LEE ,  Soo Yeon JUNG

IPC: C07D413/06 ,  C07D413/14 ,  C07D491/08 ,  C07D491/107 ,  C07D401/06

CPC classification number: C07D413/06 ,  C07D413/14 ,  C07D401/06 ,  C07D491/107 ,  C07D491/08

Abstract: The present disclosure relates to a compound derivative containing a 6-7 bicyclic ring and use thereof. The compound according to the present invention can be effectively used in the prevention or treatment of diseases caused by PRMT5 by acting as a PRMT5 inhibitor.

公开(公告)号：US20210101892A1

公开(公告)日：2021-04-08

申请号：US17102871

申请日：2020-11-24

Applicant: SK BIOPHARMACEUTICALS CO., LTD.

Inventor： Yong Je SHIN ,  Jin Hee KIM ,  Jun LEE ,  Sook Kyung PARK ,  Ho Yeon LEE ,  Hyun Suk CHOI ,  Se Hyuk KIM ,  Eun Ji KANG ,  Ho Youl LEE ,  Soo Yeon JUNG

IPC: C07D413/06 ,  C07D413/14 ,  C07D401/06 ,  C07D491/107 ,  C07D491/08

Abstract: The present disclosure relates to a compound derivative containing a 6-7 bicyclic ring and use thereof. The compound according to the present invention can be effectively used in the prevention or treatment of diseases caused by PRMT5 by acting as a PRMT5 inhibitor.