公开(公告)号：US20200377455A1

公开(公告)日：2020-12-03

申请号：US16493391

申请日：2018-03-12

Applicant: SOL-GEL TECHNOLOGIES LTD.

Inventor： Stephen CHERKEZ ,  Veera Reddy ARAVA ,  Madhusudhanarao RAYAPUREDDI ,  Venkateswarlu JASTI

IPC: C07D207/12

Abstract: The present application provides novel process for the preparation of glycopyrrolate tosylate.

公开(公告)号：US20200377456A1

公开(公告)日：2020-12-03

申请号：US16633263

申请日：2018-07-26

Applicant: SOL-GEL TECHNOLOGIES LTD.

Inventor： Veera Reddy ARAVA ,  Madhusudhanarao RAYAPUREDDI ,  Venkateswarlu JASTI

IPC: C07D207/12 ,  C07C309/30

Abstract: This invention is directed to a process for the preparation of glycopyrrolate tosylate comprising the step of reacting a halogen salt of glycopyrrolate with tosylic acid or a salt thereof in the presence of hydrogen peroxide and at least one unsaturated organic agent.