公开(公告)号：US20240270675A1

公开(公告)日：2024-08-15

申请号：US18037550

申请日：2021-02-07

Applicant: SOOCHOW UNIVERSITY

Inventor： Xiaobing WAN ,  Yonggao ZHENG ,  Suyan TAO ,  Xingxing LI ,  Xionglue CHENG

IPC: C07C67/08

CPC classification number: C07C67/08 ,  C07C2531/02

Abstract: The present invention relates to a method for preparing a carboxylic acid ester compound. Under the catalysis of nitrite, a carboxylic acid reacts with an alcohol in air so as to obtain an ester compound; and the alcohol is ethanol, propanol or trifluoroethanol. The present invention has the advantages such as mild reaction conditions, rich source of raw materials, wide universality of reaction substrates, and simple operation, and can modify a series of carboxylic acids having medicinal properties and aliphatic carboxylic acids such as biologically active amino acids.