公开(公告)号：US11136339B2

公开(公告)日：2021-10-05

申请号：US16488568

申请日：2018-04-11

Applicant: SOUTHEAST UNIVERSITY

Inventor： Xinsong Li ,  Ma Si ,  Longbing Ling

IPC: C07D519/00 ,  A61P17/06 ,  A61P19/02 ,  A61P33/06 ,  A61P35/00 ,  C07F9/655

Abstract: Disclosed are a dihydroartemisinin dimer derivative, a pharmaceutical composition, and an application thereof. The derivative is an artemisinin dimer used for drugs treating or preventing malaria caused by plasmodium, drugs treating autoimmune diseases such as lupus erythematosus, and anti-tumour drugs, which is a pharmaceutical composition prepared from the dihydroartemisinin dimer derivative and a pharmaceutically acceptable carrier.